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Potassium tert-Butylate (t-BuOK)

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Chemical Formula: C₄H₉OK


1. CAS Number(s)

  • Potassium tert-butylate: 865-47-4


2. Product Description

Potassium tert-Butylate (t-BuOK) is a strong, non-nucleophilic alkoxide base widely used in organic synthesis and polymer chemistry. Owing to its high basicity and steric hindrance, it enables rapid and selective deprotonation while minimizing side reactions, making it well suited for demanding base-catalyzed processes.


3. Typical Properties (indicative)

  • Appearance: White to off-white solid (powder or granules)

  • Assay: ≥ 98%

  • Solubility: Soluble in polar aprotic solvents; reacts with protic solvents

  • Reactivity: Very strong base, moisture- and air-sensitive


4. Typical Applications

  • Strong base for elimination and deprotonation reactions

  • Anionic polymerization initiation

  • Synthesis of pharmaceuticals and specialty intermediates

  • Base-catalyzed rearrangements and condensations


5. Industries Served

  • Pharmaceuticals & Fine Chemicals

  • Specialty Chemicals

  • Polymers & Advanced Materials


6. Packaging

  • Moisture-tight drums

  • Inert-gas protected packaging available upon request


7. Storage & Handling

Store under dry, inert conditions. Protect from moisture, air, and heat. Handle using appropriate PPE due to high reactivity.


8. Regulatory & Safety

Strong alkoxide base; corrosive. SDS and CoA available upon request.

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